|
|
|
|
|
|
|
|
||||
|
The sea urchin embryo provides a
powerful model system for the study of morphogenesis and
cadherin activity. In a study performed by Jeffrey Miller
and David McClay, three developmental events where show to
be directly related to cadherin molecules: 1) the
acquisition of cell polarity in cleavage-stage blastomeres;
2) the epithelial- mesenchymal conversion of epithelial
cells to mesodermal derivatives; and 3) the convergent
extension movements involved in constructing the
archenteron. Their data provided new insight into the
function of cadherins during various morphogenetic events
and provided building blocks for future experiments
exploring cadherin localization and adhesive activity during
development. Figure: Early sea urchin embryo
performing |
Last Modified: 26 April, 2001
[Lab
Protocols
| Students
| Cebra-Thomas
| Course
| Links
]